In the actual NFL draft, NFL teams always want the No. 1 overall pick. In fantasy football drafts, the desire of fantasy managers varies.
Some prefer to have the top selection, as it gives them their preferred target atop the draft. Others would rather draft near the end of the snake and get an earlier pick in the second round.
As such, the No. 1 overall fantasy pick can be viewed as either a blessing or a curse. But either way, fantasy managers need to make sure they get the pick right. If they don’t, their roster depth will suffer as a result.
Who are the best options for the top fantasy selection this season? Below is a look at the only five players fantasy football managers should consider taking atop the draft, starting with a running back who was a league-winner for many last season.
2025 POSITION RANKINGS: QB | RB | WR | TE | K | D/ST | Overall
No. 1 pick options in fantasy football
1. Saquon Barkley, RB, Philadelphia Eagles
Barkley was the top fantasy running back last year as he generated just the ninth 2,000-yard rushing season in NFL history. He figures to once again be a highly productive runner after averaging 3.8 yards before contact per carry — a whopping 0.5 yards better than any other running back — behind a stellar Philadelphia offensive line.
The only concern with Barkley? He had a league-high 378 touches during the regular season and added another 104 to his ledger in the postseason. Since 2010, running backs with at least 337 touches in a season have seen an average decline of 113.9 PPR points, and 3.9 fewer PPR points per game, the following season.
2. Ja’Marr Chase, WR, Cincinnati Bengals
Chase won the receiving Triple Crown in 2024, leading the league in catches (127), yards (1,708) and touchdowns (17). He could certainly do it again, given the chemistry he has shown with long-time teammate Joe Burrow and the Bengals’ high-volume passing attack.
Receiver production is generally more consistent year-to-year than running back production, so few would fault anyone for taking Chase No. 1 overall, especially in PPR leagues. But in half-PPR or standard formats, it is difficult to pass on a high-end running back given how quickly top-tier talents at the position come off the board in snake drafts.
3. Bijan Robinson, RB, Atlanta Falcons
Only two running backs had more catches than Robinson’s 61 in 2024: De’Von Achane (78) and Alvin Kamara (68). That gives Robinson one of the highest PPR floors among fantasy running backs, and his on-the-ground production (1,456 yards, 14 touchdowns) is nothing to sneeze at, either.
Like Barkley, Robinson surpassed the dreaded 337-touch mark in 2024 with 365. Robinson, 23, is much younger than the 28-year-old Barkley, which might aid him in avoiding a decline. However, he also plays in a more volatile offense that will be entrusting second-year QB Michael Penix Jr. as a full-time starter for the first time.
4. Jahmyr Gibbs, RB, Detroit Lions
Gibbs showed fantasy managers his potential as a workhorse over the final three weeks of the 2024 NFL season. With David Montgomery out, Gibbs averaged 25.7 touches and 162.3 total yards per game while scoring six total touchdowns.
While Gibbs’ ceiling is that of the No. 1 overall fantasy running back, Montgomery still figures to eat into his workload. Montgomery’s size (5-11, 224 pounds) will likely make him Dan Campbell’s preferred goal-line option. That might limit Gibbs’ upside, but it’s worth noting he had the fewest touches (302) among the consensus top-three fantasy running backs for 2025.
5. Justin Jefferson, WR, Minnesota Vikings
Jefferson has only once finished worse than the No. 6-rated wide receiver in fantasy. That came in 2023, when he played just 10 games because of a hamstring injury. As long as Jefferson remains healthy, he should be one of the best fantasy football wide receivers, which puts him in the running for the No. 1 overall pick.
Still, Jefferson seems more likely to be an early-to-mid first-round selection. The Vikings are breaking in a first-year starter at quarterback, J.J. McCarthy, so any early growing pains could impact Jefferson out of the gate. So, too, could a mild hamstring strain that is keeping Jefferson out of the early stages of Minnesota’s training camp.